Endocrine Abstracts

Introduction: Thyroid disorders are the most frequently diagnosed endocrinopathies prevalence of which is highly dependent on geographic region and age of study population.Main objective: Evaluation of thyroid function and thyroid ultrasonographic features in 48–50-year-old people from general population in Lithuania.Methods: During a 1 year period 395 randomly selected 48–50-year-aged men (169) and women (226) were enrol...

Introduction: Subacute thyroiditis (SAT) can often resolve completely; however, it has been observed that in 11.6% of patients, permanent hypothyroidism (PHT) may develop the follow-up after diagnosis. Various studies have explored the relationship between thyroid volume at the time of diagnosis, post-treatment changes in thyroid volume, steroid therapy, and the development of PHT following SAT. While some studies suggest associations, there are also data indicating that no si...

ObjectiveRadioactive iodine (RAI) therapy is widely used in both diagnosis and treatment of benign and malignant thyroid diseases. It is generally a well tolerated therapy. Bone marrow suppression is often a temporary side effect with a decrease in white blood cells and platelets up to 6–10 weeks. In this study, we aimed to examine hematological changes in patients who received RAI treatment for benign or malignant diseases of the thyroid.<p cla...

Thyroid calcifications are a difficult problem to interpret. The deposition of calcium salt crystals often indicates profound morphological changes, cell death, their rearrangement and dedifferentiation. The calcifications are not guaranteed markers of any process. There is also no data on the effect calcifications on the development of a process in the thyroid. The analysis of 67 thyroid nodules, in wich calcifications were detected during ultrasound. Macrocalcifications were...

Introduction: Serum calcium (Ca) is a major regulator of PTH secretion, but serum magnesium (Mg)also can modulate PTH secretion. Intracellular Mg depletion impairs the ability of the parathyroid to secrete PTH,which subsequently cause fall in the serum Ca concentration.Case report: A 67 year old male patient was admitted to intensive care unit because of disturbance of consciousness, due to suspected hepatic encephalopathy. In his previous history, he ha...

Introduction: Relationships between vitamin D and male fertility are not fully elucidated. Studies in infertile/subfertile subjects suggest that vitamin D status may be associated with semen parameters (1, 2). Data from healthy men is inconclusive (3, 4). Our purpose was to evaluate the andrological status and a range of biochemical, dietary and lifestyle variables in healthy men aged 18–35, living in the region of Lower Silesia (Poland) (AndroLS).M...

Introduction: The prevalence of autoimmune thyroid diseases in patients with type 1 diabetes mellitus (T1DM) is high. Thyroid hormones have a pronounced effect on the regulation of glucose homeostasis. We report patient with well controlled T1DM and good compliance, presented with severe diabetic ketoacidosis (DKA) due to thyrotoxicosis.Case report: A 15-year-old girl with well-controlled T1DM for 5 years (HbA1c<8%) had no tissue complications of dia...

Aim: In a previous study, we demonstrated elevated mean platelet volume in isolated hypogonadotrophic hypogonadism (IHH) is associated with high cardiovascular risk. Monocyte count/HDL-cholesterol ratio (MHR) is a new inflammatory marker showing cardiovascular risk. The purpose of this study is to evaluate (MHR) in men with hypogonadotrophic hypogonadism.Method: This study includes 31 men with isolated hypogonadotrophic hypogonadism without previous trea...

Introduction: A complex cocktail of endocrine-disrupting and other chemicals is ubiquitous in the modern environment. Exposure to such chemicals contributes to diseases including metabolic syndrome and infertility. The liver is the primary defence organ against xenotoxicants, but also the source of major of plasma proteins, and growth factors/hormones.Aim: To understand how chronic exposure to complex mixtures of chemicals at human and environmentally re...

Introduction: Malignant feminizing adrenal tumors are very rare occurring generally in men. The lack of gynecomastia is even rarer in those tumor secreting estrogens alone, or with other adrenal hormones especially cortisol as in the following case.Case report: A male aged 44, consulted in May 2012 for abdominal pain. Radiological assessment discovered a large tumor measuring 120×95 mm located in the left adrenal with numerous metastases (pulmonary,...